The Pharmacology tab displays a:
- Data visualization:
- Bar graph of measurement counts for targets
- Line graph of consensus pActivity values for targets
- Data table:
- Ligand (CAS RN)
- Target
- Gene
- Parameter
- pValue
- Value
- Function
- Assay
- Source
For a video walkthrough, see How to navigate pharmacology data in CAS BioFinder.
CAS Drug Intelligence
Results with the CAS Drug Intelligence icon have information on approved, investigational, or discontinued drugs with a new visual identification and overviews of regulatory status, clinical phase, indications, and targets.
Download Pharmacology
Click the Download icon to download detailed data as an Excel .xlsx file.
If available for each ligand result, the detailed download contains:
- Ligand CAS RN
- Ligand Smiles
- Ligand InChl
- Target
- Gene
- Parameter
- pValue
- Value
- Function
- Assay Name
- Assay Type
- Procedure
- Ligand Dose
- Disease
- Biological System
- Source (reference document)
View Related Data
Click a ligand's name to open the ligand window, where you can open the structure in CAS Draw, view the ligand detail, and view related data in CAS SciFinder.
Open Structure in CAS Draw
Click the Edit Structure button to open the structure in CAS Draw, where you edit the structure and start a new ligands or scaffolds search.
View in CAS SciFinder
Clicking the following options will open the relevant data from CAS SciFinder in a new tab:
-
Get Reactions: Reaction results for the CAS Registry Number.
- Synthesize: Reaction results for the query "synthesis of [CAS Registry Number]"
-
Get Retrosynthesis: Opens the Retrosynthesis Plan Options page.
- Get References: Reference results that have indexed the CAS Registry Number (appears in the results' Substances section).
- Get Suppliers: Supplier results for vendors offering the CAS Registry Number substance.
View Ligand Detail
Click the CAS Registry Number or Get Ligand Details to view the ligand detail page.
View Assay Detail
Click a View link in the Assay column to view assay details, including disease detail and ligand detail.
View Disease Detail
Click a Disease link in the Assay Detail window to view the disease's detail page.
View Ligand Detail
Click the CAS Registry Number to view the ligand detail page.
View in CAS SciFinder
Click a Source link in the data table or Assay Detail window to view the detail page for the source reference in CAS SciFinder.
View Protein Detail
Click a Target link in the data table or Assay Detail window to view the target's protein detail.